{"id":130179,"date":"2021-01-08T08:11:11","date_gmt":"2021-01-08T08:11:11","guid":{"rendered":"http:\/\/www.caravanalive.com\/?p=130179"},"modified":"2021-10-26T22:38:54","modified_gmt":"2021-10-26T17:08:54","slug":"indian-firm-bharat-biotech-will-be-commencing-phase-i-trials-of-intranasal-covid-19-vaccine-candidate-next-month","status":"publish","type":"post","link":"https:\/\/www.caravanalive.com\/?p=130179","title":{"rendered":"Indian firm Bharat Biotech Will Be Commencing Phase I Trials Of Intranasal Covid-19 Vaccine Candidate Next Month"},"content":{"rendered":"<div class=\"2a6a8c3593e6620bd92d71f585bdd19b\" data-index=\"4\" style=\"float: none; margin:10px 0 10px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6453632170035383\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<!-- NEW RESPONSIVE -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-6453632170035383\"\r\n     data-ad-slot=\"2960496911\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n\n<p>PTI reported Bharat Biotech chairman and managing director, Krishna Ella, as saying in a session of TiE Global Summit that two more facilities could be established for vaccine manufacturing including Covaxin, a vaccine for the coronavirus.&nbsp;Besides Covaxin, Bharat Biotech has been actively working on developing another vaccine, for which it tied up with Washington University School of Medicine in St Louis for the novel &#8220;chimp-adenovirus&#8221; (Chimpanzee adenovirus), a single dose intranasal vaccine for Covid-19.<\/p>\n\n\n\n<p>\u201cI think it will enter into Phase I (next month) because it is going to be a single-dose vaccine. The clinical trial process is also going to be faster.\u201d&nbsp;In September, Bharat Biotech signed a licensing agreement with Washington University School of Medicine in St. Louis for a novel chimp adenovirus, single-dose intranasal vaccine for Covid-19.<\/p>\n\n\n\n<p>With the deal, the company gained the rights to supply the vaccine in all markets except the US and Japan, as well as Europe.&nbsp;The Phase I trials of the vaccine candidate will take place at Saint Louis University\u2019s Vaccine &amp; Treatment Evaluation Unit.<\/p>\n\n\n\n<p>&#8220;BBV154 (intranasal Covid-19 vaccine), preclinical testing has been completed for toxicology, immunogenicity and challenge studies. These studies have conducted in the USA and India. Phase I human clinical trials will commence during Feb &#8211; March 2021,&#8221; an email reply from the city-based vaccine maker told.<\/p>\n\n\n\n<p>On receiving the required regulatory approval, the company will conduct further stages of trials in India.&nbsp;It also anticipates carrying out large scale manufacture of the vaccine at its GMP facility located in Genome Valley, Hyderabad, a city in the Indian state of Telangana.<\/p>\n\n\n\n<p>Krishna Ella, Chairman of Bharat Biotech had earlier said the company is focusing on the intranasal vaccine as the existing vaccines require two dose intramuscular injections and a country like India needs 2.6 billion syringes and needles which may add up\u00a0to pollution.<\/p>\n\n\n\n<p>Check out\u00a0<a href=\"http:\/\/www.womansera.com\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>entertainment news here<\/strong><\/a>.\u00a0<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>PTI reported Bharat Biotech chairman and managing director, Krishna Ella, as saying in a session of TiE Global Summit that two more facilities could be established for vaccine manufacturing including Covaxin, a vaccine for the coronavirus.&nbsp;Besides Covaxin, Bharat Biotech has been actively working on developing another vaccine, for which it tied up with Washington University [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":130180,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[{"category_id":146,"category_link":"https:\/\/www.caravanalive.com\/?cat=146","category_name":"COVID-19"},{"category_id":147,"category_link":"https:\/\/www.caravanalive.com\/?cat=147","category_name":"COVID-19"},{"category_id":143,"category_link":"https:\/\/www.caravanalive.com\/?cat=143","category_name":"Vaccine"}],"tags":[{"tag_id":893,"tag_link":"https:\/\/www.caravanalive.com\/?tag=bharat-biotech","tag_name":"bharat biotech"},{"tag_id":475,"tag_link":"https:\/\/www.caravanalive.com\/?tag=coronavirus-vaccine","tag_name":"coronavirus vaccine"},{"tag_id":894,"tag_link":"https:\/\/www.caravanalive.com\/?tag=intranasal-vaccine","tag_name":"intranasal vaccine"},{"tag_id":895,"tag_link":"https:\/\/www.caravanalive.com\/?tag=vaccine","tag_name":"vaccine"}],"class_list":["post-130179","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-coronavirus","category-covid-19-2","category-vaccine","tag-bharat-biotech","tag-coronavirus-vaccine","tag-intranasal-vaccine","tag-vaccine"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.5 - 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